Pharmacology Antiepileptic drugs/ Anticonvulsants:Classification & Mechanism of action with mnemonic

Hello Everyone. Welcome back to my channel Pharmacology Made Easy. In Todays video, we are going to learn classification & mechanism of action of various antiepileptic or antiseizure drugs.  Epilepsy- Recurrent episodes seizures  Seizure- Paroxysmal abnormal discharge from aggregate of neurons at high frequency Seizures are generally classified into two major types 1.Focal or partial seizures- occurs in 80% of patients 2.Generlised seizures Antiepileptic drugs are a diverse group of medications used in the treatment of epileptic seizures. Antiepileptics work in a number of different ways to inhibit or slow down neuronal firing to prevent seizures from occurring. This pharmacology lecture covers topics such as pathophysiology and classification of seizures, action potential, excitatory and inhibitory neurotransmission (role of glutamate and GABA), voltage-gated sodium and calcium channels, AMPA and NMDA receptors, CRMP-2 protein, SV2A protein, mechanism of action and side effects of antiepileptic drugs. Drugs mentioned include; Carbamazepine, Oxcarbazepine, Lamotrigine, Phenytoin, Topiramate, Valproic acid, Zonisamide, Gabapentin, Pregabalin, Levetiracetam, Felbamate, Tiagabine, Vigabatrin, Lacosamide, Rufinamide, Zonisamide, Brivaracetam, Perampanel, Telampanel, Phenobarbitone, Ethosuximide and Trimethandione. Thanks for watching and don't forget to SUBSCRIBE, hit the LIKE button👍 and click the BELL button🔔 for future notifications!!!