Drugs used for treatment of heart failure part 1 (MCQs)

Heart failure occurs when the heart muscle doesn't pump blood as well as it should. Blood often backs up and causes fluid to build up in the lungs and in the legs. The fluid buildup can cause shortness of breath and swelling of the legs and feet. Poor blood flow may cause the skin to appear blue or gray. In this video and its affiliated parts in the Organotropic agents section, multiple-choice questions about drugs which used for treatment of heart failure in terms of uses, common side effects, mechanism of action, drug interactions, contraindications, and many important questions that you may encounter in many exams. Drugs used for treatment of heart failure: Angiotensin-Converting Enzyme (ACE) Inhibitors Commonly prescribed include: Captopril, Enalapril, Fosinopril, Lisinopril, Perindopril, Quinapril, Ramipril, Trandolapril Angiotensin II Receptor Blockers (or Inhibitors) (Also known as ARBs or Angiotensin-2 Receptor Antagonists) Commonly prescribed include: Candesartan, Losartan, Valsartan Angiotensin-Receptor Neprilysin Inhibitors (ARNIs) ARNIs are a new drug combination of a neprilysin inhibitor and an ARB. Sacubitril/valsartan If Channel Blocker (or inhibitor) This drug class reduces the heart rate, similar to another class of drugs called beta blockers. Ivabradine Beta Blockers (Also known as Beta-Adrenergic Blocking Agents) Commonly prescribed include: Bisoprolol, Metoprolol succinate, Carvedilol, Carvedilol CR Aldosterone Antagonists Commonly prescribed include: Spironolactone, Eplerenone Hydralazine and isosorbide dinitrate (specifically benefits African-Americans with heart failure) Commonly prescribed: Hydralazine and isosorbide dinitrate (combination drug) Diuretics (Also known as water pills) Commonly prescribed include: Furosemide, Bumetanide, Torsemide, Chlorothiazide, Amiloride (Midamor Chlorthalidone, Hydrochlorothiazide or HCTZ, Indapamide, Metolazone,Triamterene foxglove plant (Digitalis) To treat the heart failure (HF) and rate control of atrial fibrillation (AF). Cardiac glycosides are a class of medications that inhibit the Na+ K+ ATPase enzyme, increasing the force of heart contractions. The most commonly prescribed cardiac glycoside is digoxin, which can be used to treat atrial fibrillation, atrial flutter, and congestive heart failure What this type of medication does: Causes the body to rid itself of excess fluids and sodium through urination. Helps to relieve the heart’s workload. Decreases the buildup of fluid in the lungs and other parts of the body, such as the ankles and legs. Different diuretics remove fluid at varied rates and through different methods . #pharmacology #mcq #chf