Resident Evil 3 Remake - Final Phase Nemesis (Inferno Mode)
This mode is insane! 1st Phase Nemesis is extremely agile and he can dodge your grenade rounds and rockets more easily. I recommend you run unless you have infinite weapons. If you earned enough points to get the Infinite Rocket Launcher, this will save you a lot of time and reloads, otherwise you may want to opt for the Infinite MUP Handgun and Assault Rifle. This was the only boss that I had to reload constantly on Nightmare and Inferno Mode since this boss is extremely aggressive. Even with 2 defense coins once you get caught with Nemesis's hand smashing combo you're dead after 3 hits. There are very rare instances that if you get hit by Nemesis' 1st attack from his hand smashing combo you may be able to recover to dodge the succeeding attacks but your dead almost all of the time. It's left or right hand swipes are less dangerous and a bit easier to dodge in my opinion. If you die you can quit the game and reload your save or load your save twice to avoid adding game time from dying. Good luck!