Shocking Truth: High B12 Linked to Cancer. Quantified B12 Levels, Cancer Types, MCAS, Mastocytosis

Do you have ongoing elevations in your vitamin B12 level? Maybe you're having a lot of concern about whether or not you might have cancer or some other bone marrow problem? In this video, we're going to go into some of those risks, specifically going to look at what are the most common types of cancer that are associated with elevated B12. **My Book: Don't B12 Deficient https://geni.us/rTQTvd (amazon link) ** Reference: https://academic.oup.com/qjmed/articl... Some of the testing and strategies you might want to consider when you have this going on, as well as some ways to look at it and understand what's going on in your body when you have ongoing elevated B12 levels Do you have ongoing elevations in your vitamin B12 level? Maybe you're having a lot of concern about whether or not you might have cancer or some other bone marrow problem?We're going to go into some of those risks, specifically going to look at what are the most common types of cancer that are associated with elevated B12. Some of the testing and strategies you might want to consider when you have this going on, as well as some ways to look at it and understand what's going on in your body when you have ongoing elevated B12 levels. High B12 on a blood test is not something that most people should or need to worry about. As I've said in previous videos, most of the time it's occurring because you're taking a B12 supplement in some shape or form. Maybe it's a multivitamin or it could be a vitamin drink or energy drink with B12 in it. The problem is what happens when that's not the case? What happens, for instance, when you haven't taken any B12 in years, either in the form of injection or oral or even vitamin drinks? That's when you want to make sure you don't have something more serious going on like cancer. And that's what I'm dedicating this video to discussing. Sort of the worst-case scenario type things. Now, I hesitate to make a video like this because in the vast majority of people, it's high for some benign reason. And a video like this may create unnecessary fear. Still, I think the opposite perspective can also be used. What if it helps someone get a diagnosis earlier? So with that, let me share some finer points about this topic. Let me first quickly start by mentioning the benign reasons for high B12, and they are, you're either taking vitamin B12, there's some genetic reason that you have elevated B12, either with the transcobalamin molecules or other genetic aspects, and then some not so benign reasons like problems with your liver, kidney, or even solid tumors in these organs. It's usually pretty straightforward to get your kidney and liver checked and to check to make sure you're not taking B12. After this though, what is the next step? What are you going to do? Well, it really depends on how long it's been high for and how high it actually is. Each case would have to be looked at on an individual basis. So here I'm attempting to give you a little more context on this topic so you can decide along with your healthcare provider when it's time to dig a little bit deeper and see, for instance, a hematologist. In the last video on high B12 or elevated B12, we discussed that B12 is carried throughout our bodies via three carrier proteins known as transcobalamins. They're made in the liver and they can also be made in white blood cells called granulocytes. These types of white blood cells increase in conditions like mast cell activation syndrome, mastocytosis, and white blood cell cancers. In all these cases, it can lead to more of the proteins that bind B12 or transcobalamins, less of the B12 getting into the cell, and more floating around in your blood, thus spiking the test. So if you have ongoing high levels of B12, what are you actually going to do? The first thing is to consider just scheduling with the hematologist. They will do and know more than you're gonna get from a video like this. You can also get a test done which was mentioned in the previous video video on Unsaturated B12 binding capacity. As mentioned in the previous video, if this is elevated outside of the lab's reference range and you also have high serum B12, it suggests an increased production of those binding proteins, those transcobalamins. In this case, your body may be making more of those granulocyte type of white blood cells. That doesn't necessarily mean it's cancer, but it also does increase the chances that it is. But things like mast cell activation, mast cell activation syndrome, and other similar disorders can also do this. Polycythemia vera, hyper eosinophilic syndrome, and cancers like chronic myeloid leukemia, primary myelofibrosis, myelodysplastic syndromes, and acute leukemias are all well-documented reasons for having elevated B12.