DHT Itch: The Connection Between Acne and Male Pattern Baldness

Join the Channel Discord:   / discord   Time Stamps: 0:08 Introduction / Explanation of what DHT itch is. 1:29 DHT and the skin at a glance 1:59 DHT Itch: Does it exist? 2:20 DHT Hair health 3:11 DHT and sebaceous glands 4:00 DHT causes over production of sebum 4:22 The Annual Changes of Clinical Manifestation of Androgenetic Alopecia Clinic in Korean Males and Females: A Outpatient-Based Study 5:00 Seborrheic Dermatitis linked to Acne and Androgenetic Alopecia 5:19 Connection between AGA and Seborrheic Dermatitis 5:40 Androgenetic alopecia in adolescents: A report of 43 cases *Topical Antiandrogens* 7:19 CB-03-01 (Clascoterone) 8:22 KX-826 (Pyrilutamide) 9:06 RU58841 10:41 My Thoughts 1. **Studies directly addressing Androgenetic Alopecia**: RU 58841, A New Specific Topical Antiandrogen: A Candidate of Choice for the Treatment of Acne, Androgenetic Alopecia and Hirsutism* https://www.sciencedirect.com/science... Percutaneous absorption of a new [RU 58841] antiandrogen included in liposomes or in solution https://www.sciencedirect.com/science... The Annual Changes of Clinical Manifestation of Androgenetic Alopecia Clinic in Korean Males and Females: A Outpatient-Based Study https://www.ncbi.nlm.nih.gov/pmc/arti... https://pubmed.ncbi.nlm.nih.gov/23717... https://sci-hub.ee/10.5021/ad.2013.25... Androgenetic alopecia in adolescents: A report of 43 cases https://pubmed.ncbi.nlm.nih.gov/17040... https://onlinelibrary.wiley.com/doi/e... To Evaluate Efficacy, Safety, and Tolerability of KX-826 in Male Subjects With Androgenetic Alopecia https://classic.clinicaltrials.gov/ct... Kintor succeeds in Phase II study of US males with androgenetic alopecia https://www.clinicaltrialsarena.com/n... COSMO ANNOUNCES THE BEGINNING OF THE PHASE III TRIALS IN MALES FOR THE TREATMENT OF ANDROGENETIC ALOPECIA https://www.cosmopharma.com/news-and-... 2. **Studies addressing treatments with potential relevance to Androgenetic Alopecia**: Pyrilutamide (KX-826): a potential FIC AR antagonist for topical dermatological use http://pdf.dfcfw.com/pdf/H3_AP2020072... 3. **Studies related to Acne**: Efficacy and Safety of Topical Clascoterone Cream, 1%, for Treatment in Patients With Facial Acne: Two Phase 3 Randomized Clinical Trials https://www.researchgate.net/publicat... Open-label, long-term extension study to evaluate the safety of clascoterone (CB-03-01) cream, 1% twice daily, in patients with acne vulgaris https://www.jaad.org/article/S0190-96... 4. **General or Foundational References**: Clascoterone https://go.drugbank.com/drugs/DB12499) Biochemistry, Dihydrotestosterone https://www.ncbi.nlm.nih.gov/books/NB...