Posology One Shot | Definition, Factors affecting Posology, Pediatric dose calculation.

Posology One Shot | Definition, Factors affecting Posology, Pediatric dose calculation. Notes 👉https://telegram.me/Vishal_aditya/1771 #Posology #Posology_one_shot #Factors_affecting_posology #pediatric_dose_calculation #Dose_calculation_based_on_age_weight_and_body_surface_area #posology_b_pharma #posology_pharmaceutics #nurturing_medicos Pharmaceutical Microbiology 3rd semester👉   • Pharmaceutica Microbiology BP303T b p...   Pharmaceutical Engineering Semester 3 Pharmaceutical Organic Chemistry -II POC-2nd  Semester 3rd Pharmaceutics-I 1st semester     • Pharmaceutics-I B pharma semester-01 ...   Pharmaceutical Inorganic chemistry IPC Semester 1st    • IPC( Inorganic pharmaceutical chemist...   Pathophysiology semester 2nd    • Pathophysiology B pharma 2nd semester   Pharmaceutical organic Chemistry POC-1 Semester 2nd    • Pharmaceutical Organic Chemistry -I (...   Human anatomy and physiology 2nd Semester 2nd     • Human Anatomy and Physiology - II   Posology, the study of medication dosages and administration, is influenced by several factors, including: 1. **Patient Characteristics**: This includes factors like age, weight, sex, and overall health. Children, for example, often require different dosages than adults due to their smaller size and developing physiology. 2. **Disease or Condition**: The specific medical condition being treated can impact posology. Some conditions may require higher or lower doses, or the use of different medications altogether. 3. **Pharmacokinetics**: This refers to how the body processes a drug, including absorption, distribution, metabolism, and excretion. These factors can affect how often a medication needs to be taken and in what form (e.g., oral, intravenous). 4. **Pharmacodynamics**: This relates to how a drug affects the body and its target. Some drugs have a narrow therapeutic window, meaning the difference between a therapeutic dose and a toxic dose is small, requiring careful dosing. 5. **Genetics**: Genetic variations can influence how an individual metabolizes and responds to drugs. Pharmacogenomics is the study of how genetics affects drug responses. 6. **Drug-Drug Interactions**: Some medications can interact with each other, either enhancing or reducing their effectiveness. Dosage adjustments may be needed when multiple medications are prescribed. 7. **Route of Administration**: Different routes of administration (e.g., oral, intravenous, topical) can affect how quickly and efficiently a drug is absorbed and distributed in the body. 8. **Tolerance**: Over time, some individuals may develop tolerance to a medication, requiring higher doses to achieve the same effect. 9. **Compliance**: Patient adherence to the prescribed dosing schedule is crucial for the effectiveness of the medication. 10. **Safety and Side Effects**: Balancing the desired therapeutic effect with potential side effects and safety concerns is essential when determining the appropriate dosage. 11. **Duration of Treatment**: The length of time a patient needs to take a medication can vary, and this affects the overall dosing strategy. #Pediatric dose calculation formulas are essential for determining the appropriate medication dosages for children, taking into account their age, weight, and other factors. Here are some commonly used pediatric dose calculation formulas: 1. **Body Surface Area (BSA)**: BSA (m²) = √[(Height in cm × Weight in kg) / 3600] Once BSA is calculated, it can be used to adjust the adult dose. Pediatric doses are often expressed as milligrams per square meter (mg/m²). 2. **Young's Rule**: Young's Rule is used to calculate pediatric doses based on a child's age. Pediatric Dose = (Age of Child / (Age of Child + 12)) × Adult Dose 3. **Clark's Rule**: Clark's Rule calculates pediatric doses based on a child's weight. Pediatric Dose = (Child's Weight in kg / 70) × Adult Dose 4. **Fried's Rule**: Fried's Rule calculates pediatric doses based on a child's age and weight. Pediatric Dose = (Age of Child in months / 150) × Adult Dose 5. **Dose per Kilogram**: This simple method calculates the pediatric dose based on the child's weight in kilograms. Pediatric Dose = (Child's Weight in kg × Adult Dose per kg) 6. **Body Mass Index (BMI)**: BMI-based dosing is used for certain medications and may require additional calculations. Pediatric Dose = (BMI × Adult Dose) ‪@NurturingMedicos‬ Share , Like and Subscribe!