Resident Evil 6 (Leon and Helena's Campaign) Chapter 2

Leon and Helena make it to the cathedral. After taking refuge, they find a gate that leads to the catacombs and they have to find a way to open it fully. They do enter the catacombs and have to solve puzzles to get through. Meanwhile, they search for Helena's sister Deborah who was taken by Simmons and then infected. When Deborah is found, she mutates and attacks Leon, Helena, and Ada. Deborah eventually does die and the duo is now wanting revenge for the death of Deborah, especially Helena.